autophagi

Meanings

• Noun

  A cellular process by which a eukaryotic cell degrades and recycles its own cytoplasm and organelles in response to nutrient starvation or other stressors.

  - "Autophagy is an essential process for survival during periods of nutrient deprivation."
  - "The autophagosome is a double-membraned vesicle that forms around cytoplasmic material during autophagy."
  - "Autophagy plays a role in removing damaged organelles and protein aggregates from the cell."

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Variants

List of all variants of autophagi that leads to same result
autophagies , autophagy

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Etymology

origin and the way in which meanings have changed throughout history.

From the Greek autophagos, meaning 'self-eater'.

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Trivia

Any details, considerations, events or pieces of information regarding the word

1. Autophagy was first discovered in starving yeast cells in the 1960s.

2. Autophagy is a conserved process found in all eukaryotic organisms, from yeast to humans.

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Related Concepts

informations on related concepts or terms closely associated with the word. Discuss semantic fields or domains that the word belongs to

1. Lysosome: Autophagosomes fuse with lysosomes to form autolysosomes, where the degradation of cellular material occurs.

2. Macroautophagy: The most common form of autophagy, characterized by the formation of double-membraned autophagosomes that engulf cytoplasmic material.

3. Microautophagy: A form of autophagy where the lysosomal membrane directly engulfs cytoplasmic material without the formation of an autophagosome.

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Culture

Any cultural, historical, or symbolic significance of the word. Explore how the word has been used in literature, art, music, or other forms of expression.

Autophagy has been studied extensively in various organisms, including yeast, flies, mice, and humans. It has been implicated in various diseases, including cancer, neurodegenerative disorders, and infections. In literature, autophagy has been described as a 'housekeeping' process that helps maintain cellular homeostasis.

How to Memorize "autophagi"

1. visualize
   

   - Imagine a cell undergoing autophagy as a self-eating machine, engulfing its own cytoplasm and organelles.

2. associate
   

   - Associate the word 'autophagy' with the idea of a cell recycling its own material.

3. mnemonics
   

   - Use the mnemonic 'Autos' for 'Autophagy' - 'Self-eater'.

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